ABSTRACT:
BACKGROUND: Hypoxic-ischemic encephalopathy (HIE) is a type of brain injury that occurs when the brain doesn't receive enough oxygen or blood flow occurring during pregnancy, labor and delivery or in the postnatal period. This study aimed at determining factors associated with preventable HIE at Kacyiru Hospital in Rwanda.
METHODS: This is a case-control study design using quantitative analysis of data records from patient records of all neonates admitted in neonatology ward for HIE from 1st January 2016 – 31st March 2018 including their mothers. Data were analyzed using STATA version 13.
RESULTS: This study showed that the majority of APGAR scores less than 7 at 1, 5 and 10 min were found in cases 79.9%, 88.8% and 100% respectively. Convulsions were mostly observed in cases (94.6%) while sucking reflex ability was more detected in controls (93.8%). The presence of Moro reflexes was also different in cases and controls, 18.1 % and 81.9% respectively. Women with stained amniotic fluids were 6 times more likely to have babies with HIE, Women presenting abnormal fetal heart tracings on CTG during labor were 18 times more likely to have babies with HIE and women who attended 0 to 2 ANC visits were 2 times more at risk of delivering babies with HIE.
CONCLUSION: Preventable HIE in term neonates at Kacyiru Hospital was likely to be associated with meconium-stained amniotic fluid, abnormal fetal heart tracing, inappropriate ANC and male gender. Since HIE treatment is only limited to supportive rather than curative., its prevention and case reduction is important.
Keywords (MeSH): Hypoxic ischemic encephalopathy; neonate; brain injury; pregnancy; term; preterm
